Cell membrane
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Illustration of a Eukaryotic cell membraneThe cell membrane (also called the plasma membrane or plasmalemma) is one biological membrane separating the interior of a cell from the outside environment.[1]
The cell membrane surrounds all cells and it is semi-permeable, controlling the movement of substances in and out of cells.[2] It contains a wide variety of biological molecules, primarily proteins and lipids, which are involved in a variety of cellular processes such as cell adhesion, ion channel conductance and cell signaling. The plasma membrane also serves as the attachment point for the intracellular cytoskeleton and, if present, the extracellular cell wall
Function
The cell membrane surrounds the protoplasm of a cell and, in animal cells, physically separates the intracellular components from the extracellular environment, thereby serving a function similar to that of skin. In fungi, some bacteria, and plants, an additional cell wall forms the outermost boundary; however, the cell wall plays mostly a mechanical support role rather than a role as a selective boundary[citation needed]. The cell membrane also plays a role in anchoring the cytoskeleton to provide shape to the cell, and in attaching to the extracellular matrix and other cells to help group cells together to form tissues. The barrier is differentially permeable and able to regulate what enters and exits the cell, thus facilitating the transport of materials needed for survival. The movement of substances across the membrane can be either passive, occurring without the input of cellular energy, or active, requiring the cell to expend energy in moving it. The membrane also maintains the cell potential.
Specific proteins embedded in the cell membrane can act as molecular signals that allow cells to communicate with each other. Protein receptors are found ubiquitously and function to receive signals from both the environment and other cells. These signals are transduced and passed in a different form into the cell. For example, a hormone binding to a receptor could open an ion channel in the receptor and allow calcium ions to flow into the cell. Other proteins on the surface of the cell membrane serve as "markers" that identify a cell to other cells. The interaction of these markers with their respective receptors forms the basis of cell-cell interaction in the immune system.